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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC4
All Species:
15.15
Human Site:
Y59
Identified Species:
23.81
UniProt:
Q9NPG8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPG8
NP_001127859.1
344
39787
Y59
A
V
H
G
L
L
H
Y
L
F
H
T
R
N
H
Chimpanzee
Pan troglodytes
XP_001142662
344
39946
Y59
A
V
H
G
L
L
H
Y
L
F
H
T
R
N
H
Rhesus Macaque
Macaca mulatta
XP_001091630
344
39843
Y59
A
M
H
R
S
L
H
Y
L
F
H
T
R
N
H
Dog
Lupus familis
XP_536886
343
39778
Y59
A
M
P
K
L
L
H
Y
L
F
R
T
R
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6H5
343
39509
Q59
A
V
Q
T
L
L
H
Q
L
F
H
T
R
H
P
Rat
Rattus norvegicus
Q5FVR1
343
39379
Q59
A
V
Q
T
L
L
H
Q
L
F
H
T
R
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506292
476
54090
H193
A
A
H
R
V
L
H
H
L
L
H
T
R
N
Y
Chicken
Gallus gallus
XP_414861
343
39066
R61
V
T
Q
K
V
L
L
R
L
F
H
T
R
N
Y
Frog
Xenopus laevis
NP_001086024
326
37591
S57
W
L
Q
R
R
Y
K
S
S
F
Q
T
R
N
G
Zebra Danio
Brachydanio rerio
NP_956343
345
39869
R61
I
C
Y
R
T
M
H
R
L
F
H
Q
R
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
G130
L
V
R
G
F
D
H
G
I
R
F
C
D
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328533
299
33861
F40
P
I
E
R
L
H
H
F
I
T
F
G
A
Y
D
Maize
Zea mays
NP_001150688
392
44335
Y71
L
V
L
G
V
E
G
Y
C
C
D
R
P
N
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBC2
397
44927
F71
V
I
L
S
V
E
Y
F
C
C
D
R
P
N
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RWM9
429
49597
T66
G
R
L
T
T
S
L
T
R
L
G
R
H
L
W
Conservation
Percent
Protein Identity:
100
98.2
94.1
77
N.A.
73.8
70.9
N.A.
45.1
50
45.6
45.5
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
100
98.8
96.5
86.6
N.A.
85.1
83.1
N.A.
54.4
66.2
63.9
61.7
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
100
100
80
73.3
N.A.
66.6
66.6
N.A.
60
46.6
26.6
40
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
86.6
80
N.A.
73.3
73.3
N.A.
80
60
33.3
60
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
25.2
25.2
N.A.
23.9
N.A.
22.1
Protein Similarity:
39.8
42.6
N.A.
41.5
N.A.
38.4
P-Site Identity:
13.3
26.6
N.A.
6.6
N.A.
0
P-Site Similarity:
33.3
33.3
N.A.
33.3
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
14
14
0
7
0
0
7
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
14
0
7
0
7
% D
% Glu:
0
0
7
0
0
14
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
14
0
60
14
0
0
0
0
% F
% Gly:
7
0
0
27
0
0
7
7
0
0
7
7
0
0
7
% G
% His:
0
0
27
0
0
7
67
7
0
0
54
0
7
14
27
% H
% Ile:
7
14
0
0
0
0
0
0
14
0
0
0
0
0
0
% I
% Lys:
0
0
0
14
0
0
7
0
0
0
0
0
0
7
0
% K
% Leu:
14
7
20
0
40
54
14
0
60
14
0
0
0
7
0
% L
% Met:
0
14
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
7
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
14
0
27
% P
% Gln:
0
0
27
0
0
0
0
14
0
0
7
7
0
0
0
% Q
% Arg:
0
7
7
34
7
0
0
14
7
7
7
20
67
0
0
% R
% Ser:
0
0
0
7
7
7
0
7
7
0
0
0
0
0
0
% S
% Thr:
0
7
0
20
14
0
0
7
0
7
0
60
0
0
0
% T
% Val:
14
40
0
0
27
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
7
0
0
7
7
34
0
0
0
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _